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The Gut-Hormone Connection: How Your Digestive Health Influences Your Menstrual Cycle

What if I told you that your gut health holds the key to how balanced and stable your hormones are throughout the month? It’s easy to think of digestion as separate from the hormonal changes that shape your menstrual cycle, but the truth is, they’re deeply connected. If you've been experiencing irregular periods, intense PMS, or unexpected mood swings, your gut health might be the missing piece of the puzzle. PMID: 39265472


Your gut isn’t just responsible for breaking down food—it’s a powerful control centre that directly impacts your hormones. When your gut is out of balance, it can throw your entire hormonal system off, leading to issues like bloating during ovulation, digestive discomfort before your period, and even more severe menstrual symptoms. Sound familiar?


In this post, we’ll dive into how gut health plays a key role in regulating hormones across each phase of your cycle, and why gut dysfunction might be the hidden factor affecting your hormonal health.


The Connection Between Gut Health and Hormonal Balance


The gut microbiome, which is made up of trillions of bacteria, is a crucial player in hormone metabolism. One of its key roles is regulating estrogen levels through a group of bacteria known as the estrobolome.

The estrobolome helps metabolise and eliminate excess estrogen from the body, ensuring that hormone levels stay in balance.

When the gut is functioning well, estrogen is properly broken down and excreted. However, if gut health is compromised—whether through inflammation, an imbalance in the gut microbiome (dysbiosis), or other gut issues—this process becomes impaired. As a result, estrogen can recirculate in the body, leading to estrogen dominance, a condition linked to PMS, heavy periods, and more.


Additionally, gut inflammation can disrupt hormone signaling throughout the body. Inflammation triggers an increase in stress hormones like cortisol, which can further throw off the delicate balance between estrogen and progesterone, intensifying menstrual symptoms.


Gut Dysfunction and Hormonal Imbalance


When gut dysfunction sets in, it creates a domino effect on hormonal health. Conditions like leaky gut, SIBO (small intestinal bacterial overgrowth), and chronic gut infections can damage the gut lining and disrupt nutrient absorption, which directly impacts hormone production.


Leaky gut allows toxins and undigested food particles to pass through the intestinal lining and into the bloodstream, causing systemic inflammation. This inflammation can suppress progesterone production while allowing estrogen levels to rise unchecked, resulting in estrogen dominance. In some cases, gut issues can lead to progesterone deficiency, which is associated with symptoms like irregular periods, mood swings, and painful menstruation.


All of this goes to say, without proper gut function, hormone imbalances can develop leading to irregularities in your cycle and worsening PMS or other symptoms.  PMID: 36421397 Let’s take a look at each phase of the menstrual cycle and the changes that can occur in the gut during each. 

1. Gut Health During the Menstrual Phase (Days 1-5)


At the start of your period, both estrogen and progesterone are at their lowest levels. This drop in hormones signals your body to shed the uterine lining, which leads to menstruation. While your body focuses on this process, other systems—including digestion—can slow down or act unpredictably.


As your period begins, it’s common to experience digestive discomfort. Prostaglandins, chemicals involved in triggering uterine contractions, also affect the digestive tract. Higher levels of prostaglandins can lead to inflammation, causing common gut issues such as:


  • Bloating: Fluid retention and hormonal shifts can lead to feelings of puffiness and discomfort.

  • Constipation or diarrhoea: Digestive motility may slow down or speed up, depending on your body's response to the drop in hormones and increase in prostaglandins.

  • Cramps and nausea: Those with poor gut health often report worse menstrual cramps, which can also cause nausea.


If you notice these symptoms worsen during your period, your gut might be contributing to the problem. When gut health is compromised, inflammation levels tend to rise, which can intensify period symptoms. An inflamed gut can worsen uterine cramping, leading to more painful periods. Additionally, if your gut isn’t efficiently processing and eliminating estrogen, it can contribute to heavier bleeding, further exacerbating the discomfort during your period.


2. Gut Health During the Follicular Phase (Days 1-13)


As the menstrual phase ends, estrogen levels gradually rise, and the body starts preparing for ovulation. This is the time when your body is focused on nurturing and growing the follicles in your ovaries. Estrogen plays a key role in this process, peaking just before ovulation.


During the follicular phase, digestive motility often increases, meaning food moves through your digestive tract faster. For many, this leads to more regular bowel movements, but those with gut imbalances may experience digestive irregularities:


  • Constipation: This can still be an issue during this phase if gut function is compromised, especially as estrogen begins to fluctuate.

  • Erratic bowel movements: May occur if your gut struggles to adapt to the hormonal changes, leading to alternating bouts of diarrhea or constipation.


A well-functioning gut is essential for metabolizing and eliminating excess estrogen. When gut health is optimal, estrogen is efficiently processed, which helps to prevent the buildup of this hormone that could lead to PMS-like symptoms later in the cycle.

3. Gut Health During the Ovulatory Phase (Days 12-16)


During ovulation, there’s a surge in luteinizing hormone (LH) that triggers the release of an egg, while estrogen reaches its peak. This brief yet powerful hormonal shift can affect the body in multiple ways, including the digestive system.


As estrogen peaks during ovulation, it can lead to temporary shifts in digestion. For those with pre-existing gut issues, the symptoms listed below can be more pronounced, causing heightened digestive discomfort.


  • Bloating (due to estrogen’s role in water retention)

  • Constipation

  • More severe digestive distress

  • Nausea


Ladies, taking care of your gut health during the ovulatory phase is essential. By maintaining a balanced microbiome, you can help ease the impact of hormonal fluctuations, minimizing discomfort and supporting a smoother transition into the luteal phase.


5. Gut Health During the Luteal Phase (Days 16-28)


During the luteal phase, progesterone becomes the dominant hormone, rising steadily to support a potential pregnancy. If no fertilization occurs, progesterone will drop at the end of this phase, signaling the onset of menstruation.


As progesterone levels rise, they naturally slow gut motility, which can lead to common digestive issues such as:


  • Constipation

  • Bloating 

  • And gas 


Gut dysfunction during the luteal phase can worsen typical PMS symptoms, including irritability, headaches, and acne. Additionally, poor gut health can contribute to fatigue during this phase, as your body becomes less efficient at absorbing nutrients and managing hormone fluctuations. 


Supporting Gut Health for Better Menstrual Health


It’s clear that maintaining a healthy gut is key to balancing hormones and ensuring a smoother menstrual cycle. The good news is, there are things we can do to reduce uncomfortable symptoms and support healthy hormones: 


1. Increase Fibre for Hormone Detox:

Fibre-rich foods like vegetables, fruits, and whole grains help bind to excess estrogen in the digestive tract, facilitating its elimination. By increasing fibre intake, you can improve the body's ability to detoxify hormones, reducing the risk of estrogen dominance and easing symptoms like bloating and PMS.

   

2. Incorporate Fermented Foods:

Fermented foods such as kimchi, sauerkraut, yogurt, and kefir introduce beneficial bacteria that help maintain a healthy gut microbiome. These probiotics support digestion, promote estrogen metabolism, and reduce inflammation, leading to a more balanced hormonal environment.


3. Stress Management to Reduce Inflammation:

Chronic stress elevates cortisol levels, which can cause gut inflammation and disrupt hormone balance. Practicing stress-reducing techniques such as meditation, yoga, deep breathing, or time in nature can help lower inflammation and promote better gut function.


4. Consider Probiotic and Prebiotic Supplementation:

Probiotics help replenish healthy gut bacteria, while prebiotics (like those found in garlic, onions, and bananas) feed those good bacteria. Together, they promote a balanced microbiome, improving both digestion and hormone regulation.


Conclusion


So, there you have it! A balanced gut not only supports digestion but also plays an important role in hormone regulation. From the menstrual to the luteal phase, maintaining gut health can help mitigate uncomfortable symptoms, promote hormonal balance, and enhance your sense of well-being. 


If you’re struggling with menstrual irregularities or uncomfortable symptoms, it might be time to consider the health of your gut. Book a free review call with me to get to the root of your symptoms and discover personalised strategies to get you back to feeling your best. 

Juliana x


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